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1 List of Publications: Articles in Refereed Journals Joel, D., Ayalon, L., Tarrasch, R., Veenman L, Feldon, J., & Weiner, I. (1998). Electrolytic lesion of globus pallidus ameliorates the behavioral and neurodegenerative effects of quinolinic acid lesion of the striatum: a potential novel treatment in a rat model of Huntington's disease. Brain Research, 787, (IF 2.55#) Ayalon, L., Hermesh, H., & Dagan, Y. (2002). Case study of circadian rhythm sleep disorder following haloperidol treatment: reversal by risperidone and melatonin. Chronobiology International, 19, (IF 3.98) Joel, D., Ayalon, L., Tarrasch, R., & Weiner, I. (2003). Deficits induced by quinolinic acid lesion to the striatum in a position discrimination and reversal task are ameliorated by permanent and temporary lesion to the globus pallidus: A potential novel treatment in a rat model of Huntington's disease. Movement Disorders, 18, (IF 4.01) Ayalon, L., Doron, R., Weiner, I., & Joel, D. (2004). Amelioration of behavioral deficits in a rat model of Huntington's disease by an excitotoxic lesion to the globus pallidus. Experimental Neurology, 186, (IF 4.14#) Dagan, Y., & Ayalon, L. (2005). Psychiatric misdiagnosis of non-24-hours sleep-wake schedule disorder resolved by melatonin. Journal of the American Academy of Child and Adolescent Psychiatry, 44(12), (IF 4.98) Borodkin, K., Ayalon, L., Kanety, H., & Dagan, Y. (2005). Dysregulation of circadian rhythms following prolactin-secreting pituitary microadenoma. Chronobiology International, 22, (IF 3.98) Drummond, S. P. A., Bischoff-Grethe, A., Dinges, D. F., Ayalon, L., Mednick, S.C., & Meloy, M. J. (2005). The neural basis of the psychomotor vigilance task. Sleep, 28, (IF 5.4) Ayalon, L., Ancoli-Israel, S., Stepnowsky, C., Palmer, B. W., Liu, L., Loredo, J. S., Corey-Bloom, J., Greenfield, D., & Cooke, J. R. (2006). Treatment adherence in patients with Alzheimer's disease and obstructive sleep apnea. American Journal of Geriatric Psychiatry, 14(2), (IF 3.35) Chong, M. S., Ayalon, L., Marler, M., Loredo, J. S., Corey-Bloom, J., Palmer, B. W., Liu, L., & Ancoli-Israel, S. (2006). Continuous positive airway pressure improves subjective daytime sleepiness in mild-moderate Alzheimer's disease patients with sleep disordered breathing. Journal of American Geriatric Society, 54, (IF 3.66)

2 Ayalon, L., Ancoli-Israel, S., Klemfuss, Z., Shalauta, M. D., & Drummond, S.P.A. (2006). Increased brain activation during verbal learning in obstructive sleep apnea. NeuroImage, 31(4), (IF 7.17#) Dimsdale J. E., Ancoli-Israel S., Ayalon L., Elsmore T., & Gruen W. (2007). Taking Fatigue Seriously II: Observations in Patients with Malignancy. Psychosomatics, 48(3), (IF 1.71) Ayalon, L., Borodkin, K., Dishon, L., Kaneti, H., & Dagan, Y. (2007). Circadian rhythm sleep disorders following mild traumatic brain injury. Neurology, 68, (IF 8.17#) Ayalon, L., Ancoli-Israel, S., & Drummond, S.P.A. (2009). Altered brain activation during response inhibition in obstructive sleep apnea. Journal of Sleep Research, 18(2), (IF 3.5) Ancoli-Israel, S. Palmer, B. P., Cooke, J. R. Corey-Bloom, J., Fiorentino, L., Natarajan, L., Liu, L., Ayalon, L., He, F., & Loredo, J. (2008). Cognitive effects of treating obstructive sleep apnea in Alzheimer s disease: A randomized controlled study. Journal of American Geriatrics Society, 56(11), (IF 3.66) Cooke, J. R., Ayalon, L., Palmer, B. W., Loredo, J. S., Corey-Bloom, J., Natarajan, L., Liu, L., & Ancoli-Israel, S. (2009). Sustained use of CPAP slows deterioration of cognition, sleep, and mood in patients with Alzheimer s disease and obstructive sleep apnea: A preliminary study. Journal of Clinical Sleep Medicine, 5(4), Ayalon, L., Ancoli-Israel, S., Aka, A. A., McKenna, B. S., & Drummond, S.P.A. (2009). Relationship between obstructive sleep apnea severity and brain activation during a shortterm attention task. Sleep, 32(3), ) IF 5.4) Brumm, K. P., Perthen. J. E., Liu, T. T., Haist, F., Ayalon, L., & Love, T. (2010). An arterial spin labeling investigation of cerebral blood flow deficits in chronic stroke survivors. NeuroImage, 51(3), (IF 7.2) Ayalon, L., Ancoli-Israel, S., & Drummond, S. P. (2010). Obstructive sleep apnea and age: A double insult to brain function? American Journal of Respiratory and Critical Care Medicine, 182(3), (IF 10.7) Book Chapters Ayalon, L., Liu, L. Q., & Ancoli-Israel, S. (2004). Diagnosing and treating sleep disorders in the older adult. Medical Clinics of North America, 88,

3 Ayalon, L., & Ancoli-Israel, S. (2005). Sleep in normal aging. In: Sleep: A Comprehensive Handbook, Lee-Chiong T. L. (Ed.) John Wiley & Sons Dagan, Y., Borodkin, K., Ayalon, L. (2005) Advanced, Delayed, Irregular and Non- Entrained Sleep Wake Disorders. In: Sleep: A Comprehensive Handbook Lee-Chiong T.L. (Ed.) John Wiley & Sons Ayalon, L., Dagan, Y., (2006) Circadian rhythm sleep disorders, in: Sleep disorders: A clinical Textbook, Ambrogetti, A. Hensley, M. J., Olson, L.G. (Eds), Quay Books MA Healthcare Limited Dagan, Y., Borodkin, K., Ayalon, L. (2009) Circadian Rhythms Sleep Disorders. In Lee- Chiong, T.L. (ed.) Sleep Medicine Essentials. Hoboken, New Jersey: Wiley-Blackwell Ayalon L., & Ancoli-Israel, S. (2009). Normal Sleep in Aging. In Lee-Chiong, T.L. (ed.) Sleep Medicine Essentials. Hoboken, New Jersey: Wiley-Blackwell Ayalon, L., & Drummond, S.P.A. (2011). Neuroimaging Studies in Obstructive Sleep Apnea, in: Sleep Apnea: Pathogenesis, Diagnosis, and Treatment. Pack, A.I. (Ed) Marcel Dekker Inc. Ayalon, L., & Ancoli-Israel, S. (2012) Normal Sleep in Aging. In: Lee-Chiong, T. L. (ed.) Wiley Guide to Sleep Medicine. Hoboken, New Jersey: Wiley-Liss. Book chapter. Reviews in Peer-reviewed Journals Ancoli-Israel, S., & Ayalon, L. (2006). Diagnosis and treatment of sleep disorders in older adults. The American Journal of Geriatric Psychiatry, 14(2), (IF 3.35) Ayalon, L., & Peterson, S. (2007).Functional central nervous system imaging in the investigation of obstructive sleep apnea. Current Opinion in Pulmonary Medicine, 13(6), (IF 2.69) Ancoli-Israel, S., Ayalon, L., & Salzman, C. (2008). Sleep in the elderly: Normal variations and common sleep disorders. Harvard Review of Psychiatry, 16, (IF 2.04) Orff, H. J., Ayalon, L., & Drummond, S. P. A. (2009). Traumatic Brain Injury (TBI) and sleep disturbance: A review of current research. Journal of Head Trauma Rehabilitation, 24(3), (IF 2.39)

4 Abstracts Ayalon, L., Joel, D., Tarrasch, R., Feldon, J., & Weiner, I. (1997). Electrolytic lesion of globus pallidus ameliorates the behavioral and neurodegenerative effects of quinolinic acid lesion of the striatum: a potential novel treatment in a rat model of Huntington's disease, Neuroscience Letters, Sup 48, S5. [Publication D1] Ayalon, L., Dishon L, & Dagan, Y. (2001). Circadian rhythm sleep disorders following minor head trauma, Chronobiology International, 18(6), [publication D12] Ayalon, L., Cohen, D., El-Dror, U., & Dagan, Y. (2003). Diagonal weight shifts during upright stance are related to sleep apnea and show diurnal variations. Sleep, 26, Supp., A429. Ayalon, L., & Dagan, Y. (2003). Psychiatric misdiagnosis of a boy with non 24-h sleep wake schedule disorders resolved by melatonin treatment. 14th Annual Meeting of the Society for Light Treatment and Biological Rhythms, Chronobiology International, 20(6). [ Publication D5] Szeinberg, A., Ayalon, L., & Dagan, Y. (2003). Melatonin improves sleep-wake schedule, social and behavioral manifestations in young healthy children with delayed sleep phase syndrome (DSPS). Sleep, 26, A150. Dagan, Y., Green, A., Szeinberg, A., Keston, D., Winner, A., & Ayalon, L. (2003). Is BMI a good predictor for sleepiness in applicants for commercial vehicle license? Sleep, 26, A441. Ayalon, L., Cohen, L., Ivry, Y., & Dagan, Y. (2004). Cognitive deficits in obstructive sleep apnea patients are correlated with nocturnal hypoxemia rather than with sleep fragmentation. Sleep, 27, A194. Ayalon, L., Drummond, S. P. A., Harrison, B. T., & Ancoli-Israel, S. (2004). Cerebral activation during a spatial working memory task in sleep apnea patients. The Ninth International Sleep and Breathing Symposium. Greenfield, D., Ayalon, L., Loredo, J., Fiorentino, L., & Ancoli-Israel, S. (2004). Continuing use of CPAP in Alzheimer's patients: Relation to depression. Sleep, 27, Ancoli-Israel, S., Ayalon, L., Greenfield, D., Gehrman, P., & Loredo, J. (2004). Sham- CPAP use prior to CPAP treatment is associated with better compliance in Alzheimer's

5 disease. Sleep, 27, 186. Ayalon, L., Palmer, B., Greenfield, D., Liu, L., Cohen-Zion, M., Corey-Bloom, J., Laredo, J., & Ancoli-Israel, S. (2004). Cognitive functioning in patients with dementia and sleep disordered breathing is related to nocturnal oxyhemoglobin saturation prior to sleep. Sleep, 27, Ayalon, L., Ancoli-Israel, S., Harrison, B. T., Shalauta, M. D., & Drummond, S. P. A. (2005). Increased cerebral activation during a spatial working memory task in sleep apnea patients. Proceedings of the American Thoracic Society, 2, A761. Ayalon, L., Ancoli-Israel, S., Harrison, T. B., Shalauta, M. D., & Drummond, S. P. A. (2005). Altered cerebral activation during a verbal learning task in sleep apnea patients. Sleep, 28, A174. [Publication D10]. Ayalon, L., Ancoli-Israel, S., Harrison, T. B., Shalauta, M. D., & Drummond, S. P. A. (2005). Altered cerebral activation during a verbal learning task in sleep apnea patients is associated with nocturnal oxygen desaturation. Sleep, 28, A175. [associated with publication D10] Ayalon, L., Ancoli-Israel, S., Klemfuss, Z., & Drummond, S. P. A. (2006). Brain function in obstructive sleep apnea: An association with age. Sleep, 29, A169. [publication D18] Rissling, M., Ayalon, L., Fiorentino, L., Dimsdale, J., Liu, L., & Ancoli-Israel, S. (2006). Relationship of menopausal status to sleep in women undergoing chemotherapy. Sleep, 29, A308. Jung, K., Ayalon, L., Loredo, J. S., Corey-Bloom, J., Palmer, B. S., Liu, L., & Ancoli- Israel, S. (2006). Influence of treating Alzheimer s patients sleep disordered breathing on the quality of caregivers sleep. Sleep, 29, A184. Ayalon, L. (2006). Brain activation in obstructive sleep apnea patients. Sleep Medicine, 7(Supp 2), 37. Drummond, S. P. A., Ayalon, L., Aloia, M. S. (2006). Individual differences predict compensatory recruitment with sleep deprivation. Journal of Sleep Research, 15, 57. Ayalon, L., Ancoli-Israel, S., McKenna, B. S., & Drummond, S. P. A. (2007). Altered cerebral activation during a response inhibition task in sleep apnea patients. Sleep, 30, A162. [publication D13]

6 Patel, M. R., Drummond, S. P. A., Ancoli-Israel, S., McKenna, B. S., & Ayalon, L. (2007). Association between apnea-hypopnea index and brain activation in obstructive sleep apnea during a short-term attention task. Sleep, 30, A18.

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